Population pharmacokinetics of meropenem in critically ill patients

Rančić Aleksandar; Milosavljević Miloš N.; Rosić Nikola; Milovanović Dragan; Folić Marko; Zečević Dejana Ružić; Petrović Nemanja; Čorbić Mirjana Milojević; Dabanović Vera; Janković Slobodan M.

doi:10.1515/med-2024-1004

Open Medicine (Jul 2024)

Population pharmacokinetics of meropenem in critically ill patients

Rančić Aleksandar,
Milosavljević Miloš N.,
Rosić Nikola,
Milovanović Dragan,
Folić Marko,
Zečević Dejana Ružić,
Petrović Nemanja,
Čorbić Mirjana Milojević,
Dabanović Vera,
Janković Slobodan M.

Affiliations

Rančić Aleksandar: Institute of Public Health Kragujevac, Kragujevac, Serbia
Milosavljević Miloš N.: Department of Pharmacology and Toxicology, Faculty of Medical Sciences, University of Kragujevac, Svetozara Markovica 69, Kragujevac, 34000, Serbia
Rosić Nikola: Clinical Pharmacology Department, University Clinical Centre Kragujevac, Kragujevac, Serbia
Milovanović Dragan: Department of Pharmacology and Toxicology, Faculty of Medical Sciences, University of Kragujevac, Svetozara Markovica 69, Kragujevac, 34000, Serbia
Folić Marko: Department of Pharmacy, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, 34000, Serbia
Zečević Dejana Ružić: Department of Pharmacology and Toxicology, Faculty of Medical Sciences, University of Kragujevac, Svetozara Markovica 69, Kragujevac, 34000, Serbia
Petrović Nemanja: Department of Pharmacology and Toxicology, Faculty of Medical Sciences, University of Kragujevac, Svetozara Markovica 69, Kragujevac, 34000, Serbia
Čorbić Mirjana Milojević: Clinical Pharmacology Department, University Clinical Centre Kragujevac, Kragujevac, Serbia
Dabanović Vera: Pharmacy Institution of Montenegro “Montefarm”, Podgorica, Montenegro
Janković Slobodan M.: Department of Pharmacology and Toxicology, Faculty of Medical Sciences, University of Kragujevac, Svetozara Markovica 69, Kragujevac, 34000, Serbia

DOI: https://doi.org/10.1515/med-2024-1004
Journal volume & issue: Vol. 19, no. 1
pp. 803 – 38

Abstract

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The pharmacokinetics of meropenem are significantly altered in critically ill patients. A population pharmacokinetic study was designed to estimate typical values of meropenem clearance in critically ill patients and evaluate potential factors of influence.

Published in Open Medicine

ISSN: 2391-5463 (Online)
Publisher: De Gruyter
Country of publisher: Poland
LCC subjects: Medicine
Website: https://www.degruyter.com/journal/key/med/html

About the journal

Abstract

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