Biological evaluation of acellular bovine bone matrix treated with NaOH

Abstract

Highlights We developed a low-cost and improved method of acellular bovine bone matrix with NaOH and the biological evaluation in vitro and in vivo was performed. Our work may provide a novelty thought and a modified method to applicate the acellular bovine bone matrix clinically better.

Keywords

• Acellular bovine bone matrix
• NaOH
• Bone graft
• Scaffold materials
• Bone defect repair