Main Group Metal Chemistry (Dec 2014)
An efficient synthesis of N-substituted pyrroles catalyzed by MgI2 etherate
Abstract
We describe a convenient and useful procedure for the synthesis of various 2,5-dimethyl-N-substituted pyrrole derivatives by the addition of 2,5-hexadione with aromatic amines, heteroaromatic amines and aliphatic amines catalyzed by MgI2 etherate (MgI2·(OEt2)n) in good to excellent yields.
Keywords