Nature Communications (Feb 2022)
Short- and long-read metagenomics of urban and rural South African gut microbiomes reveal a transitional composition and undescribed taxa
- Fiona B. Tamburini,
- Dylan Maghini,
- Ovokeraye H. Oduaran,
- Ryan Brewster,
- Michaella R. Hulley,
- Venesa Sahibdeen,
- Shane A. Norris,
- Stephen Tollman,
- Kathleen Kahn,
- Ryan G. Wagner,
- Alisha N. Wade,
- Floidy Wafawanaka,
- F. Xavier Gómez-Olivé,
- Rhian Twine,
- Zané Lombard,
- H3Africa AWI-Gen Collaborative Centre,
- Scott Hazelhurst,
- Ami S. Bhatt
Affiliations
- Fiona B. Tamburini
- Department of Genetics, Stanford University
- Dylan Maghini
- Department of Genetics, Stanford University
- Ovokeraye H. Oduaran
- Sydney Brenner Institute for Molecular Bioscience, University of the Witwatersrand
- Ryan Brewster
- School of Medicine, Stanford University
- Michaella R. Hulley
- Sydney Brenner Institute for Molecular Bioscience, University of the Witwatersrand
- Venesa Sahibdeen
- Division of Human Genetics, School of Pathology, Faculty of Health Sciences, National Health Laboratory Service & University of the Witwatersrand
- Shane A. Norris
- SAMRC Developmental Pathways for Health Research Unit, Department of Paediatrics, University of the Witwatersrand
- Stephen Tollman
- MRC/Wits Rural Public Health and Health Transitions Research Unit (Agincourt), School of Public Health, Faculty of Health Sciences, University of the Witwatersrand
- Kathleen Kahn
- MRC/Wits Rural Public Health and Health Transitions Research Unit (Agincourt), School of Public Health, Faculty of Health Sciences, University of the Witwatersrand
- Ryan G. Wagner
- MRC/Wits Rural Public Health and Health Transitions Research Unit (Agincourt), School of Public Health, Faculty of Health Sciences, University of the Witwatersrand
- Alisha N. Wade
- MRC/Wits Rural Public Health and Health Transitions Research Unit (Agincourt), School of Public Health, Faculty of Health Sciences, University of the Witwatersrand
- Floidy Wafawanaka
- MRC/Wits Rural Public Health and Health Transitions Research Unit (Agincourt), School of Public Health, Faculty of Health Sciences, University of the Witwatersrand
- F. Xavier Gómez-Olivé
- MRC/Wits Rural Public Health and Health Transitions Research Unit (Agincourt), School of Public Health, Faculty of Health Sciences, University of the Witwatersrand
- Rhian Twine
- MRC/Wits Rural Public Health and Health Transitions Research Unit (Agincourt), School of Public Health, Faculty of Health Sciences, University of the Witwatersrand
- Zané Lombard
- Division of Human Genetics, School of Pathology, Faculty of Health Sciences, National Health Laboratory Service & University of the Witwatersrand
- H3Africa AWI-Gen Collaborative Centre
- Scott Hazelhurst
- Sydney Brenner Institute for Molecular Bioscience, University of the Witwatersrand
- Ami S. Bhatt
- Department of Genetics, Stanford University
- DOI
- https://doi.org/10.1038/s41467-021-27917-x
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 18
Abstract
In this study, Wits and Stanford researchers use short- and long-read DNA sequencing to profile the gut microbiome of women living in rural and urban South Africa and identify transitional composition, high inter-individual diversity, and many undescribed taxa.
