Measures against aflatoxin B1: a brief review about the use of flavonoids and clays

Abstract

Aflatoxin B1 (AFB1) is one of the most abundant and toxic mycotoxins produced by toxigenic strains. This substance affects cell viability, inducing cell death in several human and animal cells. Measures have been taken to minimize damage caused by AFB1, including the use of flavonoids (polyphenolic compounds extracted from plants) and bentonites (a type of clay). In this review, the physicochemical characteristics of AFB1 and its effects on different cells are discussed. Furthermore, the cellular protective effects of flavonoids and bentonites are briefly reviewed. Finally, the emerging view of the economic effects caused by mycotoxins is briefly discussed, along with how flavonoids and bentonites might open new pathways to develop approaches to fight the toxic effects caused by aflatoxins.

Keywords

• Aflatoxin B1
• Flavonoids
• Clays
• Mechanism of action