Determination of oxidative stress index and total sialic acid in cattle infested with hypoderma spp.

Abstract

Hypodermosis is a parasitic disease, which is caused by larvae of Hypoderma lineatum and Hypoderma bovis flies in cattle and causes damage on the skin. It causes economic losses due to decrease in meat and milk yield, growth deficiency and being of no use in leather processing as a result of perforation of the leather. The aim of this study was to define the oxidative-antioxidative capacity and total sialic acid levels in cattle with hypodermosis. A total of 90 cattle was used in the study, among those, 30 with hypodermosis and 60 antibody-negative healthy bovine sera were used according to ELISA test results to investigate the biochemical parameters. Biochemical analysis included total oxidant capacity (TOC), total antioxidant capacity (TAC), oxidative stress index (OSI), and total sialic acid (TSA). TAC value was found to be statistically significantly lower (P<0.01), TOC, OSI and TSA values were found to be higher (P<0.05) in cattle with hypodermosis compared to the control group. It was concluded that hypodermosis caused significant changes in sialic acid concentration and oxidative-antioxidative capacity, which are indicators of acute phase response in cattle with hypodermosis. It is thought that these obtained findings can particularly contribute to determination and diagnosis of inflammation intensity in disease.

Keywords

• cattle
• hypodermosis
• oxidative stress
• total sialic acid