Nature Communications (Dec 2019)

Dynamic and tunable metabolite control for robust minimal-equipment assessment of serum zinc

  • Monica P. McNerney,
  • Cirstyn L. Michel,
  • Krishi Kishore,
  • Janet Standeven,
  • Mark P. Styczynski

DOI
https://doi.org/10.1038/s41467-019-13454-1
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 13

Abstract

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Tightly controlling cell output is challenging, which has limited development and applications of bacterial sensors. Here the authors develop tunable, fast-responding sensors to control production of metabolic pigments and use them to assess zinc deficiency in a low-cost, minimal equipment fashion.