Considerations about Reducing False-Negative PCR Test for COVID-19

Abstract

Polymerase chain reaction (PCR) for the detection of nucleic acids is the gold standard test for the diagnosis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, there is the probability of false-negative results with this test, which poses a threat to public health. Here, we highlight some important factors that should be considered for reducing the false-negative results of the SARS-CoV-2 PCR test. Copyright © 2022 Sabzevari and Nikbakht. Published by Global Health and Education Projects, Inc. This is an open-access article distributed under the terms of the Creative Commons Attribution License CC BY 4.0.

Keywords

• Polymerase Chain Reaction
• PCR Test
• SARS-CoV-2
• COVID-19
• False-Negative
• Diagnosis