Clinical Analysis and Surgical Management of Intracranial Meningiomas

Abstract

Objective: The current study analyses the patients who underwent surgical resection with intracranial meningiomas. Methods: This study reviewed the data of eighty-four patients diagnosed and operated with intracranial meningioma. The study was conducted retrospectively by analyzing the clinical characteristics and the histopathological results of the patients. Age at surgery, gender, and tumor location according to World Health Organization (WHO) 2021 tumor classification criteria were determined. Brain computed tomography and cranial magnetic resonance imaging was used to assess the tumor before operation and presence of recurrence/residual lesion at follow-up. Surgical management was evaluated according to Simpson resection grade. Results: Fifty-nine were women (70%) and 25 were men (30%). Female/male ratio was 2.36/1. The average age was 55.58 years (range: 28-79 years). The most common locations of surgical intracranial meningiomas were convexity, and parasagittal/falcine. Fifty-four (64.3%) patients with Simpson grade I and II, 26 (30.9%) with grade III, and 4 (4.8%) patients with grade IV resection were carried out. The most common histopathological results were transitional meningioma 28 (33.3%) patients, atypical 22 (26.2%) patients, meningothelial meningioma 21 (25.0%) patients. Sixty (71.4%) patients had WHO grade I tumor, 22 (26.2%) patients grade II tumor, and 2 (2.4%) patients grade III tumor. Conclusion: Although meningiomas are more common in female patients, grade II and III meningiomas show gender equality. The main goal of surgery is to remove the meningioma completely, including dura and bone if needed. Maximal safe surgical resection should be performed in surgery and preserve the patient's neurological functions.

Keywords

• intracranial meningioma
• surgical resection
• simpson resection grade
• who tumor classification