PECULIARITIES OF IMMUNITY IN PATIENTS WITH ALLERGIC RHINOSINUSITIS DEPENDING ON IMMUNE PATHOLOGICAL BACKGROUND OF ALLERGIC REACTION TRIGGERING

Abstract

The article is devoted to the research of peculiarities of immunity in patients with allergic rhinosinusitis (AR) depending on immune pathological background of allergic reaction triggering. 310 patients with AR were examined and divided into 4 types: patients with atopy, with antibody-dependent cytotoxic type, with immune complex type, with hypersensibility of slow type and the control group — 87 patients. In the groups the state of immunity and cytokine status were studied. In patients with atopy, cytotoxic and immune-complex types of rhinocinusitis activation of humoral immunity, and in patients with hypersensibility of slow type — activation of cellular immunity were revealed.

Keywords

• rhinosinusitis
• allergy
• immunity
• cytokines