Acta Cirúrgica Brasileira (Aug 2017)

Use of fibrinogen and thrombin sponge in pediatric split liver transplantation

  • Fernando Pompeu Piza Vicentine,
  • Adriano Miziara Gonzalez,
  • Barbara Burza Beninni,
  • Ramiro Anthero de Azevedo,
  • Marcelo Moura Linhares,
  • Alberto Goldenberg,
  • Gaspar de Jesus Lopes Filho,
  • Jose Luiz Martins,
  • Alcides Augusto Salzedas Netto

DOI
https://doi.org/10.1590/s0102-865020170080000009
Journal volume & issue
Vol. 32, no. 8
pp. 673 – 679

Abstract

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Abstract Purpose: To analyze the use of this sponge in pediatric patients undergoing split-liver transplantation. Methods: Retrospective study, including 35 pediatric patients undergoing split-liver transplantation, divided into two groups according to the use of the sponge: 18 patients in Group A (no sponge) and 17 in Group B (with sponge). Results: The characteristics of recipients and donors were similar. We observed greater number of reoperation due to bleeding in the wound area in Group A (10 patients - 55.5%) than in Group B (3 patients - 17.6%); p = 0.035. The median volume of red blood cells transfused in Group A was significantly higher (73.4 ± 102.38 mL/kg) than that in Group B (35.1 ± 41.67 mL/kg); p = 0.048. Regarding bile leak there was no statistical difference. Conclusion: The use of the human fibrinogen and thrombin sponge, required lower volume of red blood cell transfusion and presented lower reoperation rates due to bleeding in the wound area.

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