罕见病研究 (Jan 2024)

New Advances in the Use of 18F-FET PET in the Diagnosis and Management of Adult High-Grade Gliomas

  • HAN Qingqing,
  • LI Tuo,
  • XING Haiqun,
  • REN Chao,
  • LIU Jiahui,
  • WANG Yu,
  • MA Wenbin,
  • CHENG Xin,
  • HUO Li

DOI
https://doi.org/10.12376/j.issn.2097-0501.2024.01.013
Journal volume & issue
Vol. 3, no. 1
pp. 102 – 107

Abstract

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Gliomas are the most common primary intracranial tumors in adults, among which high-grade glioma patients are characterized by short survival and poor prognosis. The diagnosis, treatment, evaluation of effective treatments, and prognosis prediction of high-grade gliomas are of great significance for improving patient survival. Conventional enhanced magnetic resonance imaging has deficiencies in delineating tumor extent, identifying tumor progression and treatment-related changes. Therefore, there is a broad consensus to incorporate amino acid PET, and 18F-FET PET inparticular, into the diagnostic and therapeutic process of high-grade gliomas. In this article, we review the new research progress of 18F-FET PET in the diagnosis and treatment of adult high-grade glioma in recent years.

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