Nature Communications (Apr 2020)

Intercellular communication between artificial cells by allosteric amplification of a molecular signal

  • Bastiaan C. Buddingh’,
  • Janneke Elzinga,
  • Jan C. M. van Hest

DOI
https://doi.org/10.1038/s41467-020-15482-8
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 10

Abstract

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The principles of intercellular communication in multicellular organisms can be explored using artificial cells. Here, the authors report on giant vesicles which can recognize diffused chemical signals and amplify the signal by synthetic enzymatic cascades to allow signal propagation over long distances.