Targeting of VPS18 by the lysosomotropic agent RDN reverses TFE3-mediated drug resistance

• Huanmin Niu,
• Lilin Qian,
• Yanhai Luo,
• Fang Wang,
• Hongbo Zheng,
• Yanhui Gao,
• Hanbo Wang,
• Xuelei Hu,
• Huiqing Yuan,
• Hongxiang Lou

Affiliations

Huanmin Niu

Key Laboratory of Natural Products & Chemical Biology of Ministry of Education, Institute of Medical Sciences, The Second Hospital, Cheeloo College of Medicine, Shandong University

Lilin Qian

Department of Natural Product Chemistry, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University

Yanhai Luo

Key Laboratory of Natural Products & Chemical Biology of Ministry of Education, Institute of Medical Sciences, The Second Hospital, Cheeloo College of Medicine, Shandong University

Fang Wang

Key Laboratory of Natural Products & Chemical Biology of Ministry of Education, Institute of Medical Sciences, The Second Hospital, Cheeloo College of Medicine, Shandong University

Hongbo Zheng

Department of Natural Product Chemistry, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University

Yanhui Gao

Department of Natural Product Chemistry, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University

Hanbo Wang

Minimally Invasive Urology Center, Shandong Provincial Hospital

Xuelei Hu

Department of Thoracic Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University

Huiqing Yuan

Key Laboratory of Natural Products & Chemical Biology of Ministry of Education, Institute of Medical Sciences, The Second Hospital, Cheeloo College of Medicine, Shandong University

Hongxiang Lou

Department of Natural Product Chemistry, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University