Glial cell induced neural differentiation of bone marrow stromal cells

Abstract

Bone marrow stromal cells (BMSCs) have an important application prospect in the field of cell therapy for various neurodegenerative diseases, and inducing factors that regulate BMSC differentiation are proposed as a promising therapeutic strategy. In this study, we explored the effect of glial cell-derived neurotrophic factor (GDNF) on the course of BMSC differentiation.

Keywords

• alzheimer’s disease
• bone marrow stromal cells
• cell therapy
• glial cell-derived neurotrophic factor
• neuronal differentiation