Acta Biomedica Scientifica (Jul 2013)

FEATURES OF ANTIOXIDANT SYSTEM STATE IN ADOLESCENTS OF EASTERN SIBERIA IN DEPENDS ON THEIR GENDER AND ETHNIC ORIGIN

  • L. I. Kolesnikova,
  • N. A. Kurashova,
  • L. A. Grebenkina,
  • E. Y. Zagarskih,
  • A. V. Labygina,
  • M. I. Dolgikh,
  • O. A. Vanteeva,
  • O. A. Pervushina,
  • I. N. Gutnik

Journal volume & issue
Vol. 0, no. 4
pp. 136 – 140

Abstract

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This research is devoted to studying of features of antioxidant protection system in adolescent boys and girls of various ethnic groups of Eastern Siberia. Study of the peculiarities of processes of antioxidant protection of populations of people of different ethnicity, living in the same geographical conditions, is of undoubted scientific interest. It is especially important to assess metabolic status of a young, growing body to ensure in the future the preservation of reproductive ability. We biochemically evaluated 58 boys of 14-17 years old. Out of them 19 boys were Russian, 29 boys were Buryat population and 10 boys were metises. Also we biochemically evaluated 57 girls. Out of them 21 were Russian, 27 girls were Buryat population and 9 girls were metises. The materials for biochemical studies were blood serum and red cells. The total antioxidant activity of serum and the content of its components (superoxide dismutase, α-tocopherol, retinol, blood-reduced glutathione) were evaluatedbya spectrofluomphotometer «SHIMADZU-1501» (Japan). Statistical analysis was performed by parametric tests. The study was supported by grants of the President ofthe Council of the Russian Federation (Scientific School 494.2012.7). The detected features of antioxidant protection processes in observed adolescents had gender differences, also may be explained by their ethnicity and characterized by different degree of activity of metabolic processes in adolescent boys and girls of different ethnic groups of Eastern Siberia. Study the state of the antioxidant system of the organism can be used as an additional criterion for complex examination of practically healthy adolescents, which significantly enhance the representation about the adaptation possibilities of the organism to external conditions and can be a basis for effective monitoring of reproductive health in the future.

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