Nature Communications (Oct 2017)

DNA N6-methyladenine is dynamically regulated in the mouse brain following environmental stress

  • Bing Yao,
  • Ying Cheng,
  • Zhiqin Wang,
  • Yujing Li,
  • Li Chen,
  • Luoxiu Huang,
  • Wenxin Zhang,
  • Dahua Chen,
  • Hao Wu,
  • Beisha Tang,
  • Peng Jin

DOI
https://doi.org/10.1038/s41467-017-01195-y
Journal volume & issue
Vol. 8, no. 1
pp. 1 – 10

Abstract

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N6-methyladenine is a covalent epigenetic modification of the genome. Here, Yao and colleagues show that N6-methyladenine level in the mouse brain is dynamic following environmental stress, and the subsequent differential gene expression is correlated with LINE transposon expression.