Enhanced Sequence-Activity Mapping and Evolution of Artificial Metalloenzymes by Active Learning

• Tobias Vornholt,
• Mojmír Mutný,
• Gregor W. Schmidt,
• Christian Schellhaas,
• Ryo Tachibana,
• Sven Panke,
• Thomas R. Ward,
• Andreas Krause,
• Markus Jeschek

Affiliations

Tobias Vornholt

Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland

Mojmír Mutný

Department of Computer Science, ETH Zurich, Zurich, Switzerland

Gregor W. Schmidt

Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland

Christian Schellhaas

Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland

Ryo Tachibana

Department of Chemistry, University of Basel, Basel, Switzerland

Sven Panke

Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland

Thomas R. Ward

National Centre of Competence in Research (NCCR) Molecular Systems Engineering, Basel, Switzerland

Andreas Krause

Department of Computer Science, ETH Zurich, Zurich, Switzerland

Markus Jeschek

Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland