ACS Central Science (Jan 2020)
A Novel G Protein-Biased and Subtype-Selective Agonist for a G Protein-Coupled Receptor Discovered from Screening Herbal Extracts
- Bingjie Zhang,
- Simeng Zhao,
- Dehua Yang,
- Yiran Wu,
- Ye Xin,
- Haijie Cao,
- Xi-Ping Huang,
- Xiaoqing Cai,
- Wen Sun,
- Na Ye,
- Yueming Xu,
- Yao Peng,
- Suwen Zhao,
- Zhi-Jie Liu,
- Guisheng Zhong,
- Ming-Wei Wang,
- Wenqing Shui
Affiliations
- Bingjie Zhang
- iHuman Institute, ShanghaiTech University, Shanghai, China
- Simeng Zhao
- iHuman Institute, ShanghaiTech University, Shanghai, China
- Dehua Yang
- The National Center for Drug Screening and the CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China
- Yiran Wu
- iHuman Institute, ShanghaiTech University, Shanghai, China
- Ye Xin
- iHuman Institute, ShanghaiTech University, Shanghai, China
- Haijie Cao
- iHuman Institute, ShanghaiTech University, Shanghai, China
- Xi-Ping Huang
- Department of Pharmacology, NIMH Psychoactive Drug Screening Program, School of Medicine, University of North Carolina, Chapel Hill, North Carolina, United States
- Xiaoqing Cai
- The National Center for Drug Screening and the CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China
- Wen Sun
- The National Center for Drug Screening and the CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China
- Na Ye
- Jiangsu Key Laboratory of Neuropsychiatric Diseases and College of Pharmaceutical Sciences, Soochow University, Suzhou, Jiangsu, China
- Yueming Xu
- iHuman Institute, ShanghaiTech University, Shanghai, China
- Yao Peng
- iHuman Institute, ShanghaiTech University, Shanghai, China
- Suwen Zhao
- iHuman Institute, ShanghaiTech University, Shanghai, China
- Zhi-Jie Liu
- iHuman Institute, ShanghaiTech University, Shanghai, China
- Guisheng Zhong
- iHuman Institute, ShanghaiTech University, Shanghai, China
- Ming-Wei Wang
- The National Center for Drug Screening and the CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China
- Wenqing Shui
- iHuman Institute, ShanghaiTech University, Shanghai, China
- DOI
- https://doi.org/10.1021/acscentsci.9b01125
- Journal volume & issue
-
Vol. 6,
no. 2
pp. 213 – 225
Abstract
No abstracts available.
