International Journal of Infectious Diseases (Jan 2021)

Effectiveness of non-pharmaceutical interventions on COVID-19 transmission in 190 countries from 23 January to 13 April 2020

  • Yacong Bo,
  • Cui Guo,
  • Changqing Lin,
  • Yiqian Zeng,
  • Hao Bi Li,
  • Yumiao Zhang,
  • Md Shakhaoat Hossain,
  • Jimmy W.M. Chan,
  • David W. Yeung,
  • Kin On Kwok,
  • Samuel Y.S. Wong,
  • Alexis K.H. Lau,
  • Xiang Qian Lao

Journal volume & issue
Vol. 102
pp. 247 – 253

Abstract

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Background: To evaluate and compare the effectiveness of four types of non-pharmaceutical interventions (NPIs) to contain the time-varying effective reproduction number (Rt) of coronavirus disease-2019 (COVID-19). Methods: This study included 1,908,197 confirmed COVID-19 cases from 190 countries between 23 January and 13 April 2020. The implemented NPIs were categorised into four types: mandatory face mask in public, isolation or quarantine, social distancing and traffic restriction (referred to as mandatory mask, quarantine, distancing and traffic hereafter, respectively). Results: The implementations of mandatory mask, quarantine, distancing and traffic were associated with changes (95% confidence interval, CI) of −15.14% (from −21.79% to −7.93%), −11.40% (from −13.66% to −9.07%), −42.94% (from −44.24% to −41.60%) and −9.26% (from −11.46% to −7.01%) in the Rt of COVID-19 when compared with those without the implementation of the corresponding measures. Distancing and the simultaneous implementation of two or more types of NPIs seemed to be associated with a greater decrease in the Rt of COVID-19. Conclusion: Our study indicates that NPIs can significantly contain the COVID-19 pandemic. Distancing and the simultaneous implementation of two or more NPIs should be the strategic priorities for containing COVID-19.

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