Crystal Structure of Thioesterase SgcE10 Supporting Common Polyene Intermediates in 9- and 10-Membered Enediyne Core Biosynthesis

• Thibault Annaval,
• Jeffrey D. Rudolf,
• Chin-Yuan Chang,
• Jeremy R. Lohman,
• Youngchang Kim,
• Lance Bigelow,
• Robert Jedrzejczak,
• Gyorgy Babnigg,
• Andrzej Joachimiak,
• George N. Phillips,
• Ben Shen

Affiliations

Thibault Annaval

†Department of Chemistry, The Scripps Research Institute, Jupiter, Florida, United States

Jeffrey D. Rudolf

†Department of Chemistry, The Scripps Research Institute, Jupiter, Florida, United States

Chin-Yuan Chang

†Department of Chemistry, The Scripps Research Institute, Jupiter, Florida, United States

Jeremy R. Lohman

†Department of Chemistry, The Scripps Research Institute, Jupiter, Florida, United States

Youngchang Kim

∥Midwest Center for Structural Genomics, Argonne National Laboratory, Argonne, Illinois, United States

Lance Bigelow

∥Midwest Center for Structural Genomics, Argonne National Laboratory, Argonne, Illinois, United States

Robert Jedrzejczak

∥Midwest Center for Structural Genomics, Argonne National Laboratory, Argonne, Illinois, United States

Gyorgy Babnigg

∥Midwest Center for Structural Genomics, Argonne National Laboratory, Argonne, Illinois, United States

Andrzej Joachimiak

∥Midwest Center for Structural Genomics, Argonne National Laboratory, Argonne, Illinois, United States

George N. Phillips

BioSciences at Rice and Department of Chemistry, Rice University, Houston, Texas, United States

Ben Shen

†Department of Chemistry, The Scripps Research Institute, Jupiter, Florida, United States