Pathogenesis Study of Enterovirus 71 Using a Novel Human SCARB2 Knock-In Mouse Model

Yuefei Jin; Tiantian Sun; Guangyuan Zhou; Dong Li; Shuaiyin Chen; Weiguo Zhang; Xueyuan Li; Rongguang Zhang; Haiyan Yang; Guangcai Duan

doi:10.1128/mSphere.01048-20

mSphere (Apr 2021)

Pathogenesis Study of Enterovirus 71 Using a Novel Human SCARB2 Knock-In Mouse Model

Yuefei Jin,
Tiantian Sun,
Guangyuan Zhou,
Dong Li,
Shuaiyin Chen,
Weiguo Zhang,
Xueyuan Li,
Rongguang Zhang,
Haiyan Yang,
Guangcai Duan

Affiliations

Yuefei Jin: ORCiD; Department of Epidemiology, College of Public Health, Zhengzhou University, Zhengzhou, China
Tiantian Sun: Department of Epidemiology, College of Public Health, Zhengzhou University, Zhengzhou, China
Guangyuan Zhou: Department of Epidemiology, College of Public Health, Zhengzhou University, Zhengzhou, China
Dong Li: Department of Epidemiology, College of Public Health, Zhengzhou University, Zhengzhou, China
Shuaiyin Chen: Department of Epidemiology, College of Public Health, Zhengzhou University, Zhengzhou, China
Weiguo Zhang: Department of Epidemiology, College of Public Health, Zhengzhou University, Zhengzhou, China
Xueyuan Li: Department of Neurosurgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China
Rongguang Zhang: Department of Epidemiology, College of Public Health, Zhengzhou University, Zhengzhou, China
Haiyan Yang: Department of Epidemiology, College of Public Health, Zhengzhou University, Zhengzhou, China
Guangcai Duan: Department of Epidemiology, College of Public Health, Zhengzhou University, Zhengzhou, China

DOI: https://doi.org/10.1128/mSphere.01048-20
Journal volume & issue: Vol. 6, no. 2

Abstract

Read online

Enterovirus 71 (EV71) is associated with severe hand-foot-mouth disease. Recently, outbreaks of EV71 infection with high mortality have been reported in the Asia-Pacific region, posing a great challenge for global public health.

Published in mSphere

ISSN: 2379-5042 (Online)
Publisher: American Society for Microbiology
Country of publisher: United States
LCC subjects: Science: Microbiology
Website: https://journals.asm.org/journal/msphere

About the journal