Idiopathic desquamative interstitial pneumonia diagnosed using transbronchial lung cryobiopsy: A case report

Hiroshi Ishimoto; Noriho Sakamoto; Mutsumi Ozasa; Shin Tsutsui; Atsuko Hara; Takashi Kido; Hiroyuki Yamaguchi; Kazuko Yamamoto; Yasushi Obase; Yuji Ishimatsu; Hiroshi Mukae

Respiratory Medicine Case Reports (Jan 2021)

Idiopathic desquamative interstitial pneumonia diagnosed using transbronchial lung cryobiopsy: A case report

Hiroshi Ishimoto,
Noriho Sakamoto,
Mutsumi Ozasa,
Shin Tsutsui,
Atsuko Hara,
Takashi Kido,
Hiroyuki Yamaguchi,
Kazuko Yamamoto,
Yasushi Obase,
Yuji Ishimatsu,
Hiroshi Mukae

Affiliations

Hiroshi Ishimoto: Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan
Noriho Sakamoto: Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan; Corresponding author.
Mutsumi Ozasa: Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan; Department of Pathology, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan
Shin Tsutsui: Department of Radiology, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan
Atsuko Hara: Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan
Takashi Kido: Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan
Hiroyuki Yamaguchi: Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan
Kazuko Yamamoto: Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan
Yasushi Obase: Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan
Yuji Ishimatsu: Department of Nursing, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8520, Japan
Hiroshi Mukae: Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan

Journal volume & issue: Vol. 34
p. 101523

Abstract

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A 60-year-old Japanese man with a history of heavy smoking came to our hospital for a detailed examination, suspecting interstitial pneumonia because of gradually increasing dyspnea on exertion over a period of one year. Chest high-resolution computed tomography revealed ground-glass shadows with emphysematous changes. Pathological analysis of samples obtained using transbronchial lung cryobiopsy revealed an accumulation of alveolar macrophages with abundant eosinophilic cytoplasm in the alveolar space. Following a multidisciplinary discussion, the patient was diagnosed with desquamative interstitial pneumonia. To our knowledge, this is the first detailed report of desquamative interstitial pneumonia diagnosed using transbronchial lung cryobiopsy.

Published in Respiratory Medicine Case Reports

ISSN: 2213-0071 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the respiratory system
Website: http://www.journals.elsevier.com/respiratory-medicine-case-reports/

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