Advanced Science (Oct 2021)
Ten Years of EWAS
- Siyu Wei,
- Junxian Tao,
- Jing Xu,
- Xingyu Chen,
- Zhaoyang Wang,
- Nan Zhang,
- Lijiao Zuo,
- Zhe Jia,
- Haiyan Chen,
- Hongmei Sun,
- Yubo Yan,
- Mingming Zhang,
- Hongchao Lv,
- Fanwu Kong,
- Lian Duan,
- Ye Ma,
- Mingzhi Liao,
- Liangde Xu,
- Rennan Feng,
- Guiyou Liu,
- The EWAS Project,
- Yongshuai Jiang
Affiliations
- Siyu Wei
- College of Bioinformatics Science and Technology Harbin Medical University Harbin 150081 China
- Junxian Tao
- College of Bioinformatics Science and Technology Harbin Medical University Harbin 150081 China
- Jing Xu
- College of Bioinformatics Science and Technology Harbin Medical University Harbin 150081 China
- Xingyu Chen
- College of Bioinformatics Science and Technology Harbin Medical University Harbin 150081 China
- Zhaoyang Wang
- College of Bioinformatics Science and Technology Harbin Medical University Harbin 150081 China
- Nan Zhang
- College of Bioinformatics Science and Technology Harbin Medical University Harbin 150081 China
- Lijiao Zuo
- College of Bioinformatics Science and Technology Harbin Medical University Harbin 150081 China
- Zhe Jia
- College of Bioinformatics Science and Technology Harbin Medical University Harbin 150081 China
- Haiyan Chen
- College of Bioinformatics Science and Technology Harbin Medical University Harbin 150081 China
- Hongmei Sun
- College of Bioinformatics Science and Technology Harbin Medical University Harbin 150081 China
- Yubo Yan
- College of Bioinformatics Science and Technology Harbin Medical University Harbin 150081 China
- Mingming Zhang
- College of Bioinformatics Science and Technology Harbin Medical University Harbin 150081 China
- Hongchao Lv
- College of Bioinformatics Science and Technology Harbin Medical University Harbin 150081 China
- Fanwu Kong
- The EWAS Project Harbin China
- Lian Duan
- The EWAS Project Harbin China
- Ye Ma
- College of Bioinformatics Science and Technology Harbin Medical University Harbin 150081 China
- Mingzhi Liao
- The EWAS Project Harbin China
- Liangde Xu
- The EWAS Project Harbin China
- Rennan Feng
- The EWAS Project Harbin China
- Guiyou Liu
- The EWAS Project Harbin China
- The EWAS Project
- The EWAS Project Harbin China
- Yongshuai Jiang
- College of Bioinformatics Science and Technology Harbin Medical University Harbin 150081 China
- DOI
- https://doi.org/10.1002/advs.202100727
- Journal volume & issue
-
Vol. 8,
no. 20
pp. n/a – n/a
Abstract
Abstract Epigenome‐wide association study (EWAS) has been applied to analyze DNA methylation variation in complex diseases for a decade, and epigenome as a research target has gradually become a hot topic of current studies. The DNA methylation microarrays, next‐generation, and third‐generation sequencing technologies have prepared a high‐quality platform for EWAS. Here, the progress of EWAS research is reviewed, its contributions to clinical applications, and mainly describe the achievements of four typical diseases. Finally, the challenges encountered by EWAS and make bold predictions for its future development are presented.
Keywords
