Angiographic severity of coronary artery disease in patients with metabolic syndrome

Abstract

Background: Metabolic syndrome is considered one of the important factors that increases the cardiovascular risk. The objective of this study was to determine the frequency of metabolic syndrome in patients with coronary artery disease and to compare the frequency of severe coronary artery disease in patients with and without metabolic syndrome. Methodology: This descriptive study was carried out from January 2010 to July 2010 at Department of Cardiology, Punjab Institute of Cardiology, Lahore. Two hundred patients with coronary artery disease, planned to undergo coronary angiography were studied. They were divided into two groups; Group A with and Group B without metabolic syndrome. The severity of CAD on angiography was compared between the two groups. Results: The mean age of patients in group A was 54±10.3 and in group B 51.4±10.5 years. There were 70(75%) males and 24(25%) females in Group A, while 80(76%) males and 26(24%) females in group B. Frequency of metabolic syndrome in the study population was 47%. Frequency of severe coronary artery disease was 66% in Group A as compared to 46% in Group B (p=0.005). Conclusion: Frequency of metabolic syndrome is high in patients with coronary artery disease. Those with metabolic syndrome have severe coronary artery disease. Older patients have higher prevalence of metabolic syndrome and thus severe coronary artery disease.