Differentiation between the like and unlike isomers of dimethyl 3,4-di(p-anisyl)adipate using 1H NMR spectroscopy

Abstract

The differentiation between the like and unlike isomers of the title compound, achieved by combined use of ¹H NMR spectroscopy, spectral simulation and Molecular Mechanics, correlated by means of the Altona Equation (a generalized version of the Karplus Equation), is reported herein.

Keywords

• like and unlike diastereomers
• Altona Equation
• stereochemical analysis by NMR
• stereochemical analysis