Rational design of DNA nanostructures for single molecule biosensing

Mukhil Raveendran; Andrew J. Lee; Rajan Sharma; Christoph Wälti; Paolo Actis

doi:10.1038/s41467-020-18132-1

Nature Communications (Sep 2020)

Rational design of DNA nanostructures for single molecule biosensing

Mukhil Raveendran,
Andrew J. Lee,
Rajan Sharma,
Christoph Wälti,
Paolo Actis

Affiliations

Mukhil Raveendran: School of Electronic and Electrical Engineering and Pollard Institute, University of Leeds
Andrew J. Lee: School of Electronic and Electrical Engineering and Pollard Institute, University of Leeds
Rajan Sharma: School of Electronic and Electrical Engineering and Pollard Institute, University of Leeds
Christoph Wälti: School of Electronic and Electrical Engineering and Pollard Institute, University of Leeds
Paolo Actis: School of Electronic and Electrical Engineering and Pollard Institute, University of Leeds

DOI: https://doi.org/10.1038/s41467-020-18132-1
Journal volume & issue: Vol. 11, no. 1
pp. 1 – 9

Abstract

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A key attribute for modern healthcare is the ability to detect low concentrations of biomarkers. Here, the authors use nanopores and DNA origami with target-specific aptamers for detection of CRP.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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