Influência dos parâmetros funcionais respiratórios na qualidade de vida de pacientes com DPOC Influence of respiratory function parameters on the quality of life of COPD patients

Abstract

OBJETIVO: Avaliar a qualidade de vida dos pacientes com DPOC através dos questionários Medical Outcomes Study 36-item Short-Form Health Survey (SF-36) e Saint George's Respiratory Questionnaire (SGRQ), correlacionando-os com parâmetros funcionais respiratórios. MÉTODOS: Este foi um estudo transversal com 42 pacientes com DPOC. Foram utilizados um questionário específico (SGRQ) e um questionário geral (SF-36) e seus componentes sumarizados para a determinação da qualidade de vida desses pacientes. O quadro funcional foi avaliado pela espirometria, gasometria arterial e teste da caminhada de seis minutos. RESULTADOS: Dos 42 pacientes, 30 (71,4%) eram do sexo masculino e 12 (28,6%) do sexo feminino. A média de idade foi de 65,4 ± 8,0 anos. O escore médio dos componentes físico e mental sumarizados foi 37,05 ± 11,19 e 45,61 ± 15,65, respectivamente. O componente físico sumarizado correlacionou-se significativamente com o valor médio do VEF1 em L/s (r = 0,38; p = 0,012). O escore total do SGRQ correlacionou-se com o VEF1 (r = -0,50; p OBJECTIVE: To determine the quality of life of COPD patients by using the Medical Outcomes 36-item Short-Form Survey (SF-36) and the Saint George's Respiratory Questionnaire (SGRQ), correlating the scores with respiratory function parameters. METHODS: This was a cross-sectional study involving 42 COPD patients. We used the SGRQ (a specific questionnaire) and the SF-36 (a general questionnaire), together with their component summaries, in order to determine the quality of life of these patients. The functional profile was assessed by means of spirometry, arterial blood gas analysis and the six-minute walk test. RESULTS: Of the 42 patients, 30 (71.4%) were male and 12 (28.6%) were female. The mean age of the patients was 65.4 ± 8.0 years. The mean physical component summary and mean mental component summary scores were 37.05 ± 11.19 and 45.61 ± 15.65, respectively. The physical component summary correlated significantly with FEV1 in L/s (r = 0.38; p = 0.012). There was a correlation between the SGRQ total score and FEV1 (r = -0.50; p < 0.01). The SGRQ activity domain showed negative correlations with all respiratory function parameters. The multiple regression analysis showed that only FEV1 correlated significantly with the SGRQ total score, as well as with the activity domain score (r= -0.32; p = 0.04 and r = -0.34; p = 0.03, respectively). CONCLUSIONS: In COPD patients, a decline in FEV1 is associated with poorer quality of life, as evaluated using the SGRQ.

Keywords

• Doença pulmonar obstrutiva crônica
• Qualidade de vida
• Testes de função respiratória
• Pulmonary disease, chronic obstructive
• Quality of life
• Respiratory function tests