Pharmaceutics (Aug 2024)

Advances in Cyclodextrins and Their Derivatives in Nano-Delivery Systems

  • Xin-Yu Ji,
  • Yi-Xuan Zou,
  • Han-Fang Lei,
  • Yong Bi,
  • Rui Yang,
  • Ji-Hui Tang,
  • Qing-Ri Jin

DOI
https://doi.org/10.3390/pharmaceutics16081054
Journal volume & issue
Vol. 16, no. 8
p. 1054

Abstract

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The diversity of cyclodextrins and their derivatives is increasing with continuous research. In addition to monomolecular cyclodextrins with different branched chains, cyclodextrin-based polymers have emerged. The aim of this review is to summarize these innovations, with a special focus on the study of applications of cyclodextrins and their derivatives in nano-delivery systems. The areas covered include nanospheres, nano-sponges, nanogels, cyclodextrin metal–organic frameworks, liposomes, and emulsions, providing a comprehensive and in-depth understanding of the design and development of nano-delivery systems.

Keywords