Разработка и регистрация лекарственных средств (Jan 2019)

OPTIMIZATION OF HPLC METHODS FOR QUANTITATIVE DETERMINATION OF GLYCYRRHIZIC ACID IN LICORICE ROOTS

  • B. V. Brovchenko,
  • V. A. Ermakova,
  • A. N. Kuzmenko,
  • I. A. Samylina,
  • I. I. Krasnyuk (Jr.)

Journal volume & issue
Vol. 0, no. 3
pp. 162 – 165

Abstract

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Comparative evaluation of glycyrrhizic acid content in licorice roots by methods of UV-spectrophotometry (GF RF XIII) and high-performance liquid chromatography (HPLC) was carried out. Sample preparation for HPLC method of quantitative determination of glycyrrhizic acid in samples of domestic production is developed. Small selectivity of UV-spectrophotometry at determination of glycyrrhizic acid is experimentally established and perspective of HPLC method for standardization of licorice raw materials is shown.

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