Molecular insights into intra-complex signal transmission during stressosome activation

Algirdas Miksys; Lifei Fu; M. Gregor Madej; Duarte N. Guerreiro; Susann Kaltwasser; Maria Conway; Sema Ejder; Astrid Bruckmann; Jon Marles-Wright; Richard J. Lewis; Conor O’Byrne; Jan Pané-Farré; Christine Ziegler

doi:10.1038/s42003-022-03549-9

Communications Biology (Jun 2022)

Molecular insights into intra-complex signal transmission during stressosome activation

Algirdas Miksys,
Lifei Fu,
M. Gregor Madej,
Duarte N. Guerreiro,
Susann Kaltwasser,
Maria Conway,
Sema Ejder,
Astrid Bruckmann,
Jon Marles-Wright,
Richard J. Lewis,
Conor O’Byrne,
Jan Pané-Farré,
Christine Ziegler

Affiliations

Algirdas Miksys: Department of Biophysics II / Structural Biology, University of Regensburg
Lifei Fu: Department of Biophysics II / Structural Biology, University of Regensburg
M. Gregor Madej: Department of Biophysics II / Structural Biology, University of Regensburg
Duarte N. Guerreiro: Bacterial Stress Response Group, Microbiology, School of Natural Sciences & Ryan Institute, National University of Ireland Galway
Susann Kaltwasser: Department of Structural Biology, Max-Planck Institute of Biophysics
Maria Conway: Center for Synthetic Microbiology (SYNMIKRO) and Department of Chemistry, Philipps-University Marburg
Sema Ejder: School of Natural and Environmental Sciences, Newcastle University
Astrid Bruckmann: Department of Biochemistry I, University of Regensburg
Jon Marles-Wright: School of Natural and Environmental Sciences, Newcastle University
Richard J. Lewis: Newcastle University Biosciences Institute, Faculty of Medical Sciences, Newcastle University
Conor O’Byrne: Bacterial Stress Response Group, Microbiology, School of Natural Sciences & Ryan Institute, National University of Ireland Galway
Jan Pané-Farré: Center for Synthetic Microbiology (SYNMIKRO) and Department of Chemistry, Philipps-University Marburg
Christine Ziegler: Department of Biophysics II / Structural Biology, University of Regensburg

DOI: https://doi.org/10.1038/s42003-022-03549-9
Journal volume & issue: Vol. 5, no. 1
pp. 1 – 12

Abstract

Read online

Cryo-EM structures of the stress-sensing complex in Listeria innocua reveal conformational changes that initiate the signaling response to environmental stress.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

About the journal