Journal of Functional Foods (May 2019)
Young apple polyphenols postpone starch digestion in vitro and in vivo
Abstract
Type II diabetes is largely related with hyperglycemia that can be controlled through inhibition the activities of carbohydrate-hydrolyzing enzymes by dietary polyphenols. This study aims to explore the effects of young apple polyphenols (YAP) on starch digestion in vitro and in vivo by acute and 1-week intervention administrations using mice. It was found that YAP was able to inhibit the starch digestive enzymes including α-amylase and α-glucosidase, in which tannic acid and chlorogenic acid showed inhibition on α-amylase, and tannic acid and phlorizin showed inhibition on α-glucosidase. In addition, the levels of postprandial blood glucose and insulin were lowered by around 10% at a peak for the mice fed with combination of starch and YAP than that only fed with starch, which was observed for acute and 1-week administrations. Taken together, YAP may have potentials as a functional food in assisting prevention and alleviation of type II diabetes disease.