Therapeutic role of prokinetic drugs in the treatment of gastroesophageal reflux disease

Abstract

It is not for nothing that gastroesophageal reflux disease (GERD) is called the "disease of the XXI century": it is characterized by very high incidence and affects people of different age groups. Increased incidence of adenocarcinoma of the esophagus has led researchers to identify the chain of pathological changes: GERD - Barrett's esophagus - esophageal cancer. The diagnosis of the disease is complicated by atypical extraesophageal manifestations which are often associated with diagnostic errors and inadequate therapeutic measures. This in turn increases the percentage of GERD complications, especially in socially active young patients who usually do not comply with doctor's recommendations concerning lifestyle changes, having as a result a further complication of the disease.

Keywords

• гастроэзофагеальная рефлюксная болезнь
• терапия
• прокинетики
• итоприда гидрохлорид
• итомед®
• gastroesophageal reflux disease
• therapy
• prokinetics
• itopride hydrochloride
• itomed®