Emerging Infectious Diseases (Jul 2005)

SARS Coronavirus Detection Methods

  • Susanna K.P. Lau,
  • Xiao-Yan Che,
  • Kwok-Yung Yuen,
  • Beatrice H.L. Wong,
  • Vincent C.C. Cheng,
  • Gibson K.S. Woo,
  • Ivan F.N. Hung,
  • Rosana W.S. Poon,
  • Kwok-Hung Chan,
  • J.S. Malik Peiris,
  • Kwok-Yung Yuen

DOI
https://doi.org/10.3201/eid1107.041045
Journal volume & issue
Vol. 11, no. 7
pp. 1108 – 1111

Abstract

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Using clinical samples from patients with severe acute respiratory syndrome, we showed that the sensitivities of a quantitative reverse transcription–polymerase chain reaction (80% for fecal samples and 25% for urine samples) were higher than those of the polyclonal (50% and 5%) and monoclonal (35% and 8%) antibody-based nucleocapsid antigen capture enzyme-linked immunosorbent assays.

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