Nature Communications (Mar 2022)
Clinical and genomic features of Chinese lung cancer patients with germline mutations
- Wenying Peng,
- Bin Li,
- Jin Li,
- Lianpeng Chang,
- Jing Bai,
- Yuting Yi,
- Rongrong Chen,
- Yanyan Zhang,
- Chen Chen,
- Xingxiang Pu,
- Meilin Jiang,
- Jia Li,
- Rui Zhong,
- Fang Xu,
- Bolin Chen,
- Li Xu,
- Ning Wang,
- Jiaojiao Huan,
- Pingping Dai,
- Yanfang Guan,
- Ling Yang,
- Xuefeng Xia,
- Xin Yi,
- Jiayin Wang,
- Fenglei Yu,
- Lin Wu
Affiliations
- Wenying Peng
- The Second Department of Thoracic Oncology, Hunan Cancer Hospital/the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University
- Bin Li
- Department of Oncology, Xiangya Hospital, Central South University
- Jin Li
- Geneplus-Beijing
- Lianpeng Chang
- Geneplus-Beijing
- Jing Bai
- Geneplus-Beijing
- Yuting Yi
- Geneplus-Beijing
- Rongrong Chen
- Geneplus-Beijing
- Yanyan Zhang
- Geneplus-Beijing
- Chen Chen
- Geneplus-Beijing
- Xingxiang Pu
- The Second Department of Thoracic Oncology, Hunan Cancer Hospital/the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University
- Meilin Jiang
- The Second Department of Thoracic Oncology, Hunan Cancer Hospital/the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University
- Jia Li
- The Second Department of Thoracic Oncology, Hunan Cancer Hospital/the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University
- Rui Zhong
- The Second Department of Thoracic Oncology, Hunan Cancer Hospital/the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University
- Fang Xu
- The Second Department of Thoracic Oncology, Hunan Cancer Hospital/the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University
- Bolin Chen
- The Second Department of Thoracic Oncology, Hunan Cancer Hospital/the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University
- Li Xu
- The Second Department of Thoracic Oncology, Hunan Cancer Hospital/the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University
- Ning Wang
- Department of Oncology, The PLA Rocket Force Characteristic Medical Center
- Jiaojiao Huan
- Geneplus-Beijing
- Pingping Dai
- Geneplus-Beijing
- Yanfang Guan
- Geneplus-Beijing
- Ling Yang
- Geneplus-Beijing
- Xuefeng Xia
- Geneplus-Beijing
- Xin Yi
- Geneplus-Beijing
- Jiayin Wang
- Department of Computer Science and Technology, School of Electronic and Information Engineering, Xi’an Jiaotong University
- Fenglei Yu
- Department of Thoracic Surgery, The Second Xiangya Hospital of Central South University
- Lin Wu
- The Second Department of Thoracic Oncology, Hunan Cancer Hospital/the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University
- DOI
- https://doi.org/10.1038/s41467-022-28840-5
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 12
Abstract
Germline variants that predispose to lung cancer have been mostly studied in Western populations, but data from Chinese patients is lacking. Here the authors analyze lung cancer germline variants in 1794 Chinese patients, finding exclusive variants or with different frequency compared to TCGA data.
