Journal of Clinical Medicine (Dec 2020)

Multimorbidity Patterns and Unplanned Hospitalisation in a Cohort of Older Adults

  • Roselyne Akugizibwe,
  • Amaia Calderón-Larrañaga,
  • Albert Roso-Llorach,
  • Graziano Onder,
  • Alessandra Marengoni,
  • Alberto Zucchelli,
  • Debora Rizzuto,
  • Davide L. Vetrano

DOI
https://doi.org/10.3390/jcm9124001
Journal volume & issue
Vol. 9, no. 12
p. 4001

Abstract

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The presence of multiple chronic conditions (i.e., multimorbidity) increases the risk of hospitalisation in older adults. We aimed to examine the association between different multimorbidity patterns and unplanned hospitalisations over 5 years. To that end, 2,250 community-dwelling individuals aged 60 years and older from the Swedish National Study on Aging and Care in Kungsholmen (SNAC-K) were studied. Participants were grouped into six multimorbidity patterns using a fuzzy c-means cluster analysis. The associations between patterns and outcomes were tested using Cox models and negative binomial models. After 5 years, 937 (41.6%) participants experienced at least one unplanned hospitalisation. Compared to participants in the unspecific multimorbidity pattern, those in the cardiovascular diseases, anaemia and dementia pattern, the psychiatric disorders pattern and the metabolic and sleep disorders pattern presented with a higher hazard of first unplanned hospitalisation (hazard ratio range: 1.49–2.05; p p p p < 0.05 for all). Different multimorbidity patterns displayed a differential association with unplanned hospital care utilisation. These findings call for a careful primary care follow-up of older adults with complex multimorbidity patterns.

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