Mechanistic Insights into Dibasic Iminosugars as pH-Selective Pharmacological Chaperones to Stabilize Human α‑Galactosidase

• Huang-Yi Li,
• Hung-Yi Lin,
• Sheng-Kai Chang,
• Yu-Ting Chiu,
• Chung-Chien Hou,
• Tzu-Ping Ko,
• Kai-Fa Huang,
• Dau-Ming Niu,
• Wei-Chieh Cheng

Affiliations

Huang-Yi Li

Genomics Research Center, Academia Sinica, Taipei, Taiwan

Hung-Yi Lin

Genomics Research Center, Academia Sinica, Taipei, Taiwan

Sheng-Kai Chang

Department of Pediatrics, Taipei Veterans General Hospital, Taipei, Taiwan

Yu-Ting Chiu

Genomics Research Center, Academia Sinica, Taipei, Taiwan

Chung-Chien Hou

Genomics Research Center, Academia Sinica, Taipei, Taiwan

Tzu-Ping Ko

Institute of Biological Chemistry, Academia Sinica, Taipei, Taiwan

Kai-Fa Huang

Institute of Biological Chemistry, Academia Sinica, Taipei, Taiwan

Dau-Ming Niu

Department of Pediatrics, Taipei Veterans General Hospital, Taipei, Taiwan

Wei-Chieh Cheng

Genomics Research Center, Academia Sinica, Taipei, Taiwan