Elevated transpulmonary gradient and cardiac magnetic resonance-derived right ventricular remodeling predict poor outcomes in sickle cell disease

• Kim-Lien Nguyen,
• Xin Tian,
• Shoaib Alam,
• Alem Mehari,
• Steve W. Leung,
• Catherine Seamon,
• Darlene Allen,
• Caterina P. Minniti,
• Vandana Sachdev,
• Andrew E. Arai,
• Gregory J. Kato

Affiliations

Kim-Lien Nguyen

Cardiovascular and Pulmonary Branch, Lung and Blood Institute, Bethesda, MD, USA;Division of Cardiology, David Geffen School of Medicine at UCLA and VA Greater Los Angeles Healthcare System, CA, USA

Xin Tian

Office of Biostatistics Research, National Heart, Lung and Blood Institute, Bethesda, MD, USA

Shoaib Alam

Cardiovascular and Pulmonary Branch, Lung and Blood Institute, Bethesda, MD, USA

Alem Mehari

Sickle Cell Vascular Disease Section, Hematology Branch, Lung and Blood Institute, Bethesda, MD, USA;Howard University College of Medicine, Washington, DC, USA

Steve W. Leung

Cardiovascular and Pulmonary Branch, Lung and Blood Institute, Bethesda, MD, USA;Division of Cardiovascular Medicine, University of Kentucky, Lexington, KY, USA

Catherine Seamon

Sickle Cell Vascular Disease Section, Hematology Branch, Lung and Blood Institute, Bethesda, MD, USA

Darlene Allen

Sickle Cell Vascular Disease Section, Hematology Branch, Lung and Blood Institute, Bethesda, MD, USA

Caterina P. Minniti

Sickle Cell Vascular Disease Section, Hematology Branch, Lung and Blood Institute, Bethesda, MD, USA;Division of Hematology/Oncology, Sickle Cell Center, Montefiore Medical Center, New York, NY, USA

Vandana Sachdev

Cardiovascular and Pulmonary Branch, Lung and Blood Institute, Bethesda, MD, USA

Andrew E. Arai

Cardiovascular and Pulmonary Branch, Lung and Blood Institute, Bethesda, MD, USA

Gregory J. Kato

Sickle Cell Vascular Disease Section, Hematology Branch, Lung and Blood Institute, Bethesda, MD, USA;Division of Hematology/Oncology and Adult Sickle Cell Center of Excellence, University of Pittsburgh, PA, USA