Therapeutic Advances in Psychopharmacology (Aug 2023)

Managing medical and psychiatric multimorbidity in older patients

  • David M. Carlson,
  • Brandon C. Yarns

DOI
https://doi.org/10.1177/20451253231195274
Journal volume & issue
Vol. 13

Abstract

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Aging increases susceptibility both to psychiatric and medical disorders through a variety of processes ranging from biochemical to pharmacologic to societal. Interactions between aging-related brain changes, emotional and psychological symptoms, and social factors contribute to multimorbidity – the presence of two or more chronic conditions in an individual – which requires a more patient-centered, holistic approach than used in traditional single-disease treatment guidelines. Optimal treatment of older adults with psychiatric and medical multimorbidity necessitates an appreciation and understanding of the links between biological, psychological, and social factors – including trauma and racism – that underlie physical and psychiatric multimorbidity in older adults, all of which are the topic of this review.