Modern Trends in Analysis of Cholera Vibrios Metabolism and Nutrient Requirements

Abstract

Modern insights into cholera vibrios physiology in different life conditions are considered in the review. Described are metabolic peculiarities of V. cholerae growing on nutrient media and in vivo, as well as in cholera patient organism, with special emphasis on alterations of pathogenicity factors synthesis at different stages of the disease. Considered is biofilm role in V. cholerae preservation in inter-epidemic period. Regulation of cholera vibrios growth is shown to depend upon environmental signals which shift metabolism and alter nutrient requirements.

Keywords

• cholera vibrios
• growth medium
• metabolism
• physiology