Iranian Journal of Reproductive Medicine (Jan 2011)

Successful pregnancy following the transfer of vitrified blastocyst which developed from poor quality embryos on day 3

  • Xiao-jian Zhang,
  • Ye-zhou Yang,
  • Li-hua Min,
  • Qun Lv,
  • Pin Bai,
  • Xiao-jie Li,
  • Mei-xu Liao

Journal volume & issue
Vol. 9, no. 3
pp. 203 – 208

Abstract

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Background: The selection of pre-embryos for transferred is based on morphological appearance. But some poor quality cleaved embryos also can be cultured to the blastocyst stage and implanted.Objective: To assess the clinical pregnancy outcomes of blastocyst transfer which developed from poor quality embryos. Materials and Methods: A total of 109 cleaved embryos with poor quality were cultured to day 5/day 6 and 27 (24.8%) blastocysts were collected from the 15 cycles/patients undergoing conventional IVF. All the blastocysts were cooling with fast-freezing. Then the blastocysts were warmed for transfer. Results: All of 25 vitrified blastocysts (92.6%) survived after warming and were transferred to 15 patients. Five of the women became pregnant. Conclusion: Our results suggest that vitrified human day 5/day 6 blastocyst transfer which develop from poor quality embryo at day 3 can contribute to increasing cumulative pregnancy rates in assisted reproduction

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