Dermatologica Sinica (Dec 2016)
Systemic follicular lymphoma mimicking typical histological pattern of mycosis fungoides
Abstract
Follicular lymphoma (FL) is typically presented in the form of lymphadenopathy, hepatosplenomegaly, and bone marrow infiltration. Herein, we report a case of systemic FL first presenting with a generalized asymptomatic rash with histological features of a superficial band-like lymphoid infiltrate and areas of epidermotropism. Immunohistological studies revealed a B-cell lineage of the atypical lymphocytes. FL was diagnosed through a flow cytometric analysis of the bone marrow aspirate. As per our literature review, this is the first reported case of a systemic FL with secondary cutaneous involvement mimicking the stereotypical histological pattern of mycosis fungoides.
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