Efficacy and safety of pranoprofen in the treatment of keratoconjunctivitis sicca

Abstract

AIM: To investigate the effect and safety of pranoprofen treatment of keratoconjunctivitis sicca. METHODS: Totally 100 cases(200 eyes)of keratoconjunctivitis sicca treated in our hospital in January 2014 to May 2016 were divided into control group and study group according to different treatment methods. The patients in the control group were treated with artificial tear and the patients in the study group were treated with artificial tear combined with pranoprofen eye drops. The clinical effects of the two groups were observed and analyzed. RESULTS: In the study group, 20 cases(40 eyes)were cured, 26 cases(52 eyes)were effective. The total effective rate was 92.0% higher than that of the control group. The difference was statistically significant(PPP>0.05). The symptoms and FL scores of study group after treatment were lower than those of the control group after treatment, the BUT score was higher than that of the control group(PPP=1.00). CONCLUSION: Pranoprofen has a significant effect on the treatment of keratoconjunctivitis sicca, can improve symptoms and signs, control the infection, with high safety.

Keywords

• pranoprofen
• keratoconjunctivitis sicca
• artificial tears
• symptom
• safety
• safety