A New Cubitane Diterpenoid from the Soft Coral <em>Sinularia crassa</em>

Abstract

A new cubitane diterpenoid, crassalone A (<strong>1</strong>), was isolated from the marine soft coral <em>Sinularia crassa</em>. The structure was determined by extensive spectroscopic analyses. Compound <strong>1</strong> is not cytotoxic (IC₅₀ > 20 μg/mL) toward the four human cancer cell lines tested (HL60, MDA-MB-231, HCT-116 and <em>DLD-1</em>).

Keywords

• diterpenes
• soft coral
• &lt;em&gt;Sinularia crassa&lt;/em&gt;