Nature Communications (Jan 2020)

Microchannel network hydrogel induced ischemic blood perfusion connection

  • Jung Bok Lee,
  • Dae-Hyun Kim,
  • Jeong-Kee Yoon,
  • Dan Bi Park,
  • Hye-Seon Kim,
  • Young Min Shin,
  • Wooyeol Baek,
  • Mi-Lan Kang,
  • Hyun Jung Kim,
  • Hak-Joon Sung

DOI
https://doi.org/10.1038/s41467-020-14480-0
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 14

Abstract

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Restoration of blood flow to damaged sites has commonly involved treatment with pro-angiogenic molecules but these have undesired side effects. Here the authors present a microchannel-patterned gelatin hydrogel that is able to rescue mouse and porcine models of hindlimb ischemia.