Late Diagnosis of Disseminated <i>Sporothrix brasiliensis</i> Infection with Bone Marrow Involvement in an HIV-Negative Patient

Abstract

Sporotrichosis is a fungal disease that causes symptoms similar to those of other infectious and non-infectious diseases, making diagnosis difficult and challenging. Here, we report a case of an HIV-negative patient presenting disseminated sporotrichosis with widespread cutaneous lesions mimicking pyoderma gangrenosum, with bone marrow infection, pancytopenia, and hemophagocytic syndrome. However, all the clinical manifestations and a bacterial coinfection delayed the request for a fungal diagnosis. Therefore, sporotrichosis should always be investigated in patients from endemic areas presenting with widespread cutaneous lesions associated with pancytopenia.

Keywords

• systemic sporotrichosis
• pyoderma gangrenosum
• hemophagocytic syndrome