Romanian Neurosurgery (Dec 2011)
Computational hemodynamics in a patient - specific cerebral aneurysms models
Abstract
Backgrounds: Hemodinamic factors are known to play an important role in initiation, growth and rupture of intracerebral aneurysms. Thorough knowledge of hemodynamic parameters in cerebral arteries and aneurysms are very useful in understanding of pathophysiology and clinical evaluation of cerebral aneurysms. We describe a methodology of computational analysis of hemodinamics in a patient specific aneurysms models. Aneurysms are segmented from CT angiography images. Method: A total of 6 cerebral aneurysms models were developed from CT angiography images. A computational fluid dynamics analyses were accomplished under realistic flow conditions. We selected only patients with multiple intracerebral aneurysms and conducted hemodynamic studies in un-ruptured aneurysms. We tried to evaluate the rupture risks for these aneurysms. In our series were five middle cerebral artery aneurysm and one basilar artery aneurysm. Results: We succeed to set up a methodology in patient specific aneurysms models hemodynamic study. Computational analyses of hemodynamic factors were performed for each of these 6 aneurysms models. The results were then processed to determine the average pressure on the arterial wall and inside the aneurysm, stream lines and region of greater impact of hemodynamic forces. Conclusions: Wall shear stress plays an important role in initiation, growth and rupture of cerebral aneurysms. In vivo measurements of WSS values had become most popularly in last decade. Aneurysm geometry influences the characteristics of flow conditions.
