MLL-AF9 leukemias are sensitive to PARP1 inhibitors combined with cytotoxic drugs

• Silvia Maifrede,
• Esteban Martinez,
• Margaret Nieborowska-Skorska,
• Daniela Di Marcantonio,
• Michael Hulse,
• Bac Viet Le,
• Huaqing Zhao,
• Katarzyna Piwocka,
• Italo Tempera,
• Stephen M. Sykes,
• Tomasz Skorski

Affiliations

Silvia Maifrede

Department of Microbiology and Immunology, Temple University Lewis Katz School of Medicine, Philadelphia, PA;

Esteban Martinez

Blood Cell Development and Function Program, Research Institute of Fox Chase Cancer Center, Philadelphia, PA;

Margaret Nieborowska-Skorska

Department of Microbiology and Immunology, Temple University Lewis Katz School of Medicine, Philadelphia, PA;

Daniela Di Marcantonio

Blood Cell Development and Function Program, Research Institute of Fox Chase Cancer Center, Philadelphia, PA;

Michael Hulse

Fels Institute for Cancer Research and Molecular Biology, Temple University Lewis Katz School of Medicine, Philadelphia, PA;

Bac Viet Le

Department of Microbiology and Immunology, Temple University Lewis Katz School of Medicine, Philadelphia, PA;; Laboratory of Cytometry, Nencki Institute of Experimental Biology, Warsaw, Poland; and

Huaqing Zhao

Department of Clinical Sciences, Temple University Lewis Katz School of Medicine, Philadelphia, PA

Katarzyna Piwocka

Laboratory of Cytometry, Nencki Institute of Experimental Biology, Warsaw, Poland; and

Italo Tempera

Fels Institute for Cancer Research and Molecular Biology, Temple University Lewis Katz School of Medicine, Philadelphia, PA;

Stephen M. Sykes

Blood Cell Development and Function Program, Research Institute of Fox Chase Cancer Center, Philadelphia, PA;

Tomasz Skorski

Department of Microbiology and Immunology, Temple University Lewis Katz School of Medicine, Philadelphia, PA;; Blood Cell Development and Function Program, Research Institute of Fox Chase Cancer Center, Philadelphia, PA;; Tomasz Skorski, Department of Microbiology and Immunology and Fels Institute for Cancer Research & Molecular Biology, Temple University School of Medicine, 3400 N. Broad St, MRB 548, Philadelphia, PA 19140;