ACS Central Science (Jul 2020)

Targeted Degradation of Oncogenic KRASG12C by VHL-Recruiting PROTACs

Michael J. Bond,
Ling Chu,
Dhanusha A. Nalawansha,
Ke Li,
Craig M. Crews

Affiliations

Michael J. Bond: Department of Pharmacology, Yale University, New Haven, Connecticut, United States
Ling Chu: Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, Connecticut, United States
Dhanusha A. Nalawansha: Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, Connecticut, United States
Ke Li: Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, Connecticut, United States
Craig M. Crews: Department of Pharmacology, Yale University, New Haven, Connecticut, United States

DOI: https://doi.org/10.1021/acscentsci.0c00411
Journal volume & issue: Vol. 6, no. 8
pp. 1367 – 1375

Abstract

No abstracts available.

Published in ACS Central Science

ISSN: 2374-7951 (Online)
Publisher: American Chemical Society
Country of publisher: United States
LCC subjects: Science: Chemistry
Website: https://pubs.acs.org/journal/acscii

About the journal