mSphere (Jun 2021)
IMMUNO-COV v2.0: Development and Validation of a High-Throughput Clinical Assay for Measuring SARS-CoV-2-Neutralizing Antibody Titers
- Rianna Vandergaast,
- Timothy Carey,
- Samantha Reiter,
- Chase Lathrum,
- Patrycja Lech,
- Clement Gnanadurai,
- Michelle Haselton,
- Jason Buehler,
- Riya Narjari,
- Luke Schnebeck,
- Anne Roesler,
- Kara Sevola,
- Lukkana Suksanpaisan,
- Alice Bexon,
- Shruthi Naik,
- Bethany Brunton,
- Scott C. Weaver,
- Grace Rafael,
- Sheryl Tran,
- Alina Baum,
- Christos A. Kyratsous,
- Kah Whye Peng,
- Stephen J. Russell
Affiliations
- Rianna Vandergaast
- ORCiD
- Imanis Life Sciences, Rochester, Minnesota, USA
- Timothy Carey
- Imanis Life Sciences, Rochester, Minnesota, USA
- Samantha Reiter
- Imanis Life Sciences, Rochester, Minnesota, USA
- Chase Lathrum
- Imanis Life Sciences, Rochester, Minnesota, USA
- Patrycja Lech
- Imanis Life Sciences, Rochester, Minnesota, USA
- Clement Gnanadurai
- Imanis Life Sciences, Rochester, Minnesota, USA
- Michelle Haselton
- Imanis Life Sciences, Rochester, Minnesota, USA
- Jason Buehler
- Imanis Life Sciences, Rochester, Minnesota, USA
- Riya Narjari
- Imanis Life Sciences, Rochester, Minnesota, USA
- Luke Schnebeck
- Imanis Life Sciences, Rochester, Minnesota, USA
- Anne Roesler
- Imanis Life Sciences, Rochester, Minnesota, USA
- Kara Sevola
- Imanis Life Sciences, Rochester, Minnesota, USA
- Lukkana Suksanpaisan
- Imanis Life Sciences, Rochester, Minnesota, USA
- Alice Bexon
- Vyriad, Inc., Rochester, Minnesota, USA
- Shruthi Naik
- Vyriad, Inc., Rochester, Minnesota, USA
- Bethany Brunton
- Vyriad, Inc., Rochester, Minnesota, USA
- Scott C. Weaver
- World Reference Center for Emerging Viruses and Arboviruses, University of Texas Medical Branch, Galveston, Texas, USA
- Grace Rafael
- World Reference Center for Emerging Viruses and Arboviruses, University of Texas Medical Branch, Galveston, Texas, USA
- Sheryl Tran
- Vyriad, Inc., Rochester, Minnesota, USA
- Alina Baum
- Regeneron Pharmaceuticals Inc., Tarrytown, New York, USA
- Christos A. Kyratsous
- Regeneron Pharmaceuticals Inc., Tarrytown, New York, USA
- Kah Whye Peng
- Imanis Life Sciences, Rochester, Minnesota, USA
- Stephen J. Russell
- Imanis Life Sciences, Rochester, Minnesota, USA
- DOI
- https://doi.org/10.1128/mSphere.00170-21
- Journal volume & issue
-
Vol. 6,
no. 3
Abstract
Since its emergence at the end of 2019, SARS-CoV-2, the causative agent of COVID-19, has caused over 100 million infections and 2.4 million deaths worldwide. Recently, countries have begun administering approved COVID-19 vaccines, which elicit strong immune responses and prevent disease in most vaccinated individuals.
